Fourteen studies in total (n=1,543), of which 13 were randomised and one was non-randomised..
Amnioinfusion improved the ability of the foetus to tolerate labour (foetal distress OR 0.40, 95% CI: 0.21, 0.76), decreased the incidence of meconium below the cords (OR 0.16, 95% CI: 0.07, 0.36) and decreased the rate of Caesarean delivery (OR 0.56, 95% CI: 0.32, 0.99). There was a significant lack of homogeneity between the studies (p=0.05).
No benefits associated with the use of warmers or pumps were demonstrated. In multiple regression analysis, infusion pumps were associated with a significantly increased risk of foetal distress (R=0.83, p=0.01)