Five RCTs were included (179 patients in total).
Patients with pulmonary exacerbations (4 RCTs): pooled OR 0.37 (95% CI: 0.19, 0.74).
Patients with decreased respiratory Pseudomona load (4 RCTs): pooled OR 0.09 (95% CI: 0.03, 0.32).
Patients with Pseudomonas strains resistant to nebulised antibiotic (4 RCTs): pooled OR 3.56 (95% CI: 0.98, 12.88).
Overall effect of nebulised antipseudomonal therapy on: normalised FEV1 (% mean predicted) 8.6 (95% CI: 4.6, 12.6); normalised FVC (% mean predicted) 7.3 (95% CI: 3.1, 11.5).