Study designs of evaluations included in the review
Intervention studies were included (no further information given).
Specific interventions included in the review
Thyroxine (thyroid substitution therapy) of 4 to 106 weeks in duration.
Participants included in the review
Patients with either subclinical or overt hypothyroidism were included.
Outcomes assessed in the review
The outcome was the decrease in total cholesterol after thyroid substitution therapy.
How were decisions on the relevance of primary studies made?
The authors do not state how the papers were selected for the review, or how many of the authors performed the selection. Included studies had to report TSH levels before and after treatment, and be written in English, French or German.