Study designs of evaluations included in the review
Randomised controlled trials (RCTs) and controlled clinical trials. Patients were divided into groups as case and controls, or each individual had one eye allocated as a case and the other as a control.
Specific interventions included in the review
Medical, surgical and specific drugs (timolol, epinephrine, pilocarpine and acetolamide).
Participants included in the review
Patients that had an intraocular pressure (IOP) lower than 30 mmHg at recruitment were included.
Outcomes assessed in the review
Diagnosis of glaucoma at the end of follow-up (9 months to 15 years).
How were decisions on the relevance of primary studies made?
How the criteria were applied is not stated but all studies had to assess a pharmacological treatment in the prevention of glaucoma and patients had to have an IOP lower than 30 mmHg.