Study designs of evaluations included in the review
Randomised controlled trials (RCTs; with more than 100 participants in mifepristone studies), cohort studies and case series were included.
Specific interventions included in the review
Mifepristone in combination with a prostaglandin, and methotrexate with or without a prostaglandin.
Participants included in the review
Women undergoing medical abortion (gestational limit ranged from 49 to 63 days) were included.
Outcomes assessed in the review
The outcomes were complete abortions, blood transfusion, vomiting, diarrhoea and the use of narcotics for analgesia.
How were decisions on the relevance of primary studies made?
One reviewer made decisions on study relevance. The studies had to include regimens of mifepristone in combination with a prostaglandin and methotorexate with or without a prostaglandin.