Study designs of evaluations included in the review
Both open and double-blind trials were included in the review. No details were provided of the method used to allocate the patients to the groups. Uncontrolled studies were also included.
Specific interventions included in the review
The combination of oral aspirin (in doses ranging from 650 to 900 mg) and oral metoclopramide (10 mg per dose) was compared with either placebo, oral sumatriptan or oral dihydroergotamine.
Participants included in the review
Patients with migraine were included.
Outcomes assessed in the review
The main outcomes were the impacts on headache, nausea and vomiting. Adverse effects were also considered.
How were decisions on the relevance of primary studies made?
The authors do not state how the papers were selected for the review, or how many of the authors performed the selection.