Twelve RCTs comparing sevoflurane vs isoflurane (total n=1761).
Seven RCTs comparing sevoflurane vs propofol (total n=922).
Mean differences between sevoflurane and isoflurane:
Emergence -2.9 min(95% CI: -3.1, -2.7).
Response to commands -3.0 min (95% CI: -3.3, -2.7).
Extubation -1.6 min (95% CI: -1.9, -1.3).
Orientation -4.5 min (95% CI: -4.8, -4.2).
First analgesic -8.9 min (95% CI: -10.8, -7.0).
Discharge from recovery room 0.7 min (95% CI: -2.7, 4.1).
Mean difference between sevoflurane and propofol:
Emergence -1.2 min (95% CI: -1.3, -1.1).
Response to commands -1.4 min (95% CI: -1.5, -1.3).
Extubation -1.5 min (95% CI: -2.0, -1.1).
Orientation -1.5 min (95% CI: -1.6, -1.4).
Discharge from recovery room -0.7 min (95% CI: -2.1, 0.8).