Fourteen cohort studies were included in the review. The authors did not report the number of participants.
For people with a personal history of cancer, the LR of a positive self-reported family history of cancer among a first-degree relative was 23.0 (95% CI: 8.1, 64.0) for colon cancer, 41.0 (95% CI: 23.0, 75.0) for breast cancer, 20.0 (95% CI: 4.3, 89.0) for endometrial cancer, 44.0 (95% CI: 15.0, 132.0) for ovarian cancer, and 24.0 (95% CI: 2.3, 262.0) for prostate cancer.
For people with a personal history of cancer, the LR of a negative self-reported family history of cancer among a first-degree relative was 0.29 (95% CI: 0.13, 0.67) for colon cancer, 0.07 (95% CI: 0.03, 0.13) for breast cancer, 0.55 (95% CI: 0.35, 0.86) for endometrial cancer, 0.21 (95% CI: 0.12, 0.37) for ovarian cancer, and 0.25 (95% CI: 0.16, 0.39) for prostate cancer.
For people without a personal history of cancer, the LR of a positive self-reported family history of cancer among a first-degree relative was 23.0 (95% CI: 6.4, 81.0) for colon cancer, 8.9 (95% CI: 5.4, 15) for breast cancer, 14.0 (95% CI: 2.2, 83.4) for endometrial cancer, 34.0 (95% CI: 5.7, 202.0) for ovarian cancer, and 12.3 (95% CI: 6.5, 24.0) for prostate cancer.
For people without a personal history of cancer, the LR of a negative self-reported family history of cancer among a first-degree relative was 0.25 (95% CI: 0.10, 0.63) for colon cancer, 0.20 (95% CI: 0.08, 0.49) for breast cancer, 0.68 (95% CI: 0.31, 1.52) for endometrial cancer, 0.51 (95% CI: 0.13, 2.10) for ovarian cancer, and 0.32 (95% CI: 0.18, 0.55) for prostate cancer.