A total of seven studies (n=1,061) were included in the meta-analysis. The median STARD quality score was 0.72 (range 0.62 to 0.95).
Both sensitivity and specificity values for low-dose CT were statistically homogeneous; sensitivity p=0.9 and specificity p=0.615.
The overall pooled sensitivity was 0.966 (95% CI: 0.950, 0.978). Overall pooled specificity was 0.949 (95% CI: 0.920, 0.970)
The AUC was 99.32 per cent (standard error 0.0016)