Seven trials (4,521 women) were available. Trial quality was considered sufficient by the authors, but most studies did not avoid partial or differential verification.
Hysterosalpingography had a sensitivity of 53% (95% CI 50 to 57) and specificity of 87% (95% CI 86 to 88) for diagnosing tubal pathology and 46% (95% CI 41 to 51) and 95% (95% CI 0.94 to 0.95) for bilateral tubal pathology.
"Low-risk clinical history" increased sensitivity from 38% to 61% for any tubal pathology (p=0.005), and from 13% to 47% for bilateral tubal pathology (p=0.01) but other factors (age, duration, body mass index, type (primary/secondary), HxPID, and CAT) were not significantly associated.
Results were sensitive to imputation with sensitivities of 70% (95% CI 66 to 74) and 66% (95% CI 55 to 75) for tubal pathology prior to imputation. Of 4,521 data points, 2,632 were imputed as these women did not have laparoscopy data