Three studies (397 participants, range 78 to 210) were included in the review: one retrospective and two prospective studies.
Pooled estimates: Sensitivity was 97.0% (95% CI 93.2 to 99.1%), specificity was 98.9% (95% CI 97.0 to 99.7%), positive predictive value was 97.8% (95% CI 94.2 to 99.5%), negative predictive value was 98.5% (95% CI 96.6 to 99.5%) and overall accuracy was 98.2% (95% CI 96.6 to 99.2%).
Pathologies associated with the four false negative results observed were a 6mm parietal arteriovenous malformation, an arteriovenous malformation (<1cm), an arteriovenous fistula (<1cm) and a 2mm distal middle cerebral artery aneurysm.