(This commentary was not written by CRD, but by the authors of the DH Register).
1) This is a reworking of the 1978 Office of Technology Assessment paper featuring a newer vaccine, but more conservative assumptions about its protective effect.
2) The quality of the new evidence, as in the original study, is uncertain.
3) The parameters investigated by the sensitivity analysis were not adequately justified.
4) There were no health omissions.