(This commentary was not written by CRD, but by the authors of the DH Register).
1) The study uses cohort data concerning the morbidity and mortality associated with dental infections haematologically transferred to the hip. There is no data on the efficacy of antibiotics to prevent this: evidence is taken from bacterial endocarditis prevention.
2) The medical evidence is highly uncertain and this is reflected by the wide range in the sensitivity analysis.
3) Normal life-expectancy is assigned to lives saved, this may be optimistic.
4) There were no health omissions.