The histologic examination revealed prostate adenocarcinoma in 26.5% of cases, benign prostate hypertrophy in 64% of cases, acute and/or chronic phlogosis in 8.5% of cases and granulomatosic prostatitis in 1% of cases. The diagnostic sensitivity, specificity and accuracy were 92.5%, 78.3%, 79.3% respectively for the EDR. The corresponding figures for PSA with cut-off 4 ng/ml were 91%, 78.3% and 90%, respectively. The corresponding figures for PSA with cut-off 10 ng/ml were 80.2%, 93.3% and 90% respectively. The corresponding figures for echography were 100%, 30.3% and 48.6%, respectively.
When the different methods were combined, the sensitivity, specificity and accuracy were, respectively: 98.8%, 60% and 77%, for EDR + PSA (cut-off 4 ng/ml),
98.8%, 65.8% and 79.9% for EDR + PSA (cut-off 10 ng/ml),
100%, 22% and 64.2% for EDR + echograph,
100%, 20% and 62.9% for echograph +PSA (cut-off 4 ng/ml),
100%, 26.6% and 64.9% for echograph + PSA (cut-off 10 ng/ml).
The number of biopsies which would have been necessary if only two methods of screening had been implemented was 251 with EDR and echograph, 246 with EDR and PSA (cut-off 4 ng/ml) and 158 with EDR and PSA (cut-off 10 ng/ml).