The results for the GERD positive group were as follows.
The symptom intensity for chest pain improved significantly during the administration of omeprazole compared with placebo, (p<0.0005).
Eighteen patients had a positive omeprazole test: 12 (52%) had complete resolution of their chest pain during the treatment period and 6 (26%) had at least 50% improvement in their chest pain.
During the administration of placebo, 11 (50%) had no improvement in the reported symptom score of their chest pain, whereas 5 (23%) had at least 50% improvement in their chest pain. A placebo effect was seen, where 11 (50%) patients reported some improvement in their chest pain during placebo administration.
The results for the GERD negative group were as follows.
The symptom intensity for chest pain was similar during administration of omeprazole and placebo.
Two patients had a positive omeprazole test: 1 patient had complete resolution of chest pain during the treatment period, which was significantly less than in the GERD-positive group (no p-value reported) and 1 patient had at least 50% improvement in chest pain.
During the administration of placebo, only 1 patient had complete resolution of their chest pain.
The sensitivity of the omeprazole test was 78.3% (95% confidence interval: 61.4 - 95.1) and the specificity was 85.7% (95% confidence interval: 67.4 - 100).