The mean symptom scores were 4 (SD=2) and 1 (SD=1) for the 2 years pre- and post-intervention, respectively, (p<0.001).
The corresponding values for other outcome measures were as follows:
therapeutic score, 4 (SD=3) and 3 (SD=1), (p=0.007);
compliance score, 1(SD=1) and 3 (SD=1), (p<0.001);
theophyllin level in the blood, 5.6 (SD=3.5) and 9.2 (SD=4.8) microg/mL, (p=0.01);
autonomy score, 0 (SD=1) and 2 (SD=2), (p<0.001);
number of hospital admissions, 1 (SD=2) and 0 (SD=0), (p<0.001); and
number of days in hospital, 17 (SD=20) and 2 (SD=8), (p<0.001).
The correlation (r) between the symptom score and compliance score was significant (r=0.499, p<0.001). No significant correlation was found between the symptom and therapeutic scores.