The results of the review were as follows:
75% of children complete the monovalent HBV series, and 95% complete the separate Hib series.
Compliance with maternal screening averaged 85%.
The risk for HBV infection varied between 0.2 and 2.2 depending on age.
The type of acute HBV infection was asymptomatic (0.6-0.9), symptomatic (0.099-0.398) or fulminant infection (0.001-0.005).
The outcome of non-fulminant infection was recovery from infection (0.07-0.96), chronic carrier infection (0.08-0.9), or chronic active hepatitis (CAH)(0.01-0.03).
The outcome of fulminant acute hepatitis was death from hepatitis (0.7), recovery and/or immunity (0.06-0.09), chronic carrier or CAH (0.21-0.24).
The outcome of carrier state was CAH (1.2-5.4), cirrhosis (0.7-5.3), or hepatoma (0.5-6.1).
The outcome of CAH state was cirrhosis (20) or hepatoma (5).
The incidence of Hib infection varied between 10 and 100 cases per 100,000 population per year.
The proportion of patients with meningitis varied between 0.3 and 0.6.
The proportion of patients with epiglottitis varied between 0 and 0.42.
The proportion of patients with other Hib-related disease varied between 0.28 and 0.44.
The mortality due to meningitis varied between 0.02 and 0.08.
The mortality due to epiglottitis was 0.03.
The mortality due to other Hib-related disease was 0.02.
The probability of neurologic sequelae of Hib meningitis was 0.3.
The probability of severe neurologic sequelae of Hib meningitis varied between 0 and 0.09.