The results were as follows:
The incidence of anomalous fetuses was 1.4%.
The sensitivity of detection for structural abnormalities in early pregnancy was 59% (95% CI: 46.5 - 72.4) and the specificity was 99.9%.
When the first and second trimester were combined, the sensitivity of detection for structural abnormalities in early pregnancy was 81% (95% CI: 67.7 - 89.2).
The most common structural abnormalities diagnosed in early pregnancy were central nervous system defects (43%) and cystic hygromas (35%).
There were 37 fetuses with a structural abnormality in early pregnancy.
The detection rate of fetal abnormalities by anatomical system was: central nervous system defects (84%), neck anomalies (100%), gastrointestinal (100%), renal defects (60%), spina bifida (0%), heart anomalies (40%) and limb defects (0%).
14 fetuses with an anatomical abnormality were detected in the second trimester, 5 in the third trimester and 7 after birth.
There were 43 chromosomal abnormalities in the study group, including 23 cases of trisomy 21.