An average cost-effectiveness analysis was performed to combine costs and benefits.
The cost of treatment per admission avoided was 8 (range: 1 - 47), with a net monetary saving to the NHS of 80 (range: 0 - 157) per severe case treated.
The estimated cost-effectiveness ratio was sensitive only to variations in the cost of hospital admission: the mean savings varied between 58 and 85.
The overall savings estimated in England over five years were 437,800 (range: 3,700 - 1,078,100), which could increase if all potentially eligible patients were to be treated and if a discount rate of 3% (rather than 6%) was used.