The following outcomes were used as input parameters to the model:
probability that the patients may have a pancreatic disease = 0.1;
probability of performing repeat biopsy = 0.7;
probability of performing CT after obtaining an optimal negative un-enhanced US scan = 0.85;
probability of performing CT after obtaining a sub-optimal negative un-enhanced US scan = 0.95;
probability of performing CT after obtaining an optimal negative US scan with SonoRx = 0.6;
probability of performing CT after obtaining an optimal positive un-enhanced US scan = 0.825;
probability of performing CT scan after obtaining an optimal un-enhanced US scan = 1.0;
probability of performing CT scan after obtaining an optimal positive US scan with SonoRx = 0.75;
probability of diagnosis after positive biopsy = 1.0;
probability of diagnosis after positive repeat biopsy = 1.0;
probability of diagnosis after negative repeat biopsy = 0.85;
probability of diagnosis after obtaining a negative repeat CT scan = 0.945;
probability of diagnosis after obtaining a negative CT scan following a positive US scan = 0.25;
probability of diagnosis after obtaining a negative CT scan following a negative US scan = 0.95;
probability of diagnosis after obtaining an optimal negative US scan without CT = 0.75;
probability of diagnosis after obtaining a sub-optimal negative US scan without CT = 0.75;
probability of obtaining an optimal un-enhanced US scan = 0.2;
probability of obtaining an optimal US scan with SonoRx = 0.7;
sensitivity of biopsy = 0.9; sensitivity of CT = 0.88;
sensitivity of optimal US = 0.84;
sensitivity of sub-optimal US = 0.6;
the specificity of biopsy = 0.85;
specificity of CT = 0.91;
specificity of optimal US = 0.86;
specificity of sub-optimal US = 0.75.