The LDL-C level went from 97 (standard deviation, SD=17) to 111 (SD=17) mg/dL at week 12, (p=0.001).
Total cholesterol went from 171 (SD=21) to 186 (SD=21) mg/dL at week 12, (p=0.001).
HDL-C was unchanged, initially 47 (SD=12) mg/dL and then 47 (SD=11) mg/dL at week 12.
Triglycerides went from 136 (SD=66) to 141 (SD=78) mg/dL at week 12, (p=0.262).
Three patients reported muscle soreness and two of these withdrew from the study.
One patient had a myocardial infarction at week 5 and withdrew from the study.
The proportion of patients at the LDL-C goal level was 87% at enrolment and 68% at week 12.
Forty-two per cent of the patients were indifferent about the two drug regimens, while 13% preferred the twice-weekly regimen and 45% preferred the once-daily regimen.