Interventions:
The intervention was described clearly.
Effectiveness/Benefits:
The methods used to identify relevant studies from which to derive effectiveness were not reported. For this reason it is not possible to ascertain the validity of these estimates given the limited information provided by the author. The level of reporting was not sufficient.
Costs:
The costs included did not reflect the perspective adopted since only the drug costs were included in the analysis. The costing methods were fairly well reported, with unit costs being provided separately. The price year was not reported, so it will not be possible to revalue the results in future years.
Results and Analysis:
The results were reported clearly. A one-way sensitivity analysis was conducted on key parameters in the model. However, it would have been more appropriate to conduct a multi-way sensitivity analysis to address uncertainty in the model. The author acknowledged certain limitations of the study.
Concluding remarks:
There were a few limitations to the study methodology. Although the author's conclusions reflect the analysis undertaken, they should be considered with a degree of caution.