The expected QALYs for the target population were 21,239,159 for no screening. Compared with no screening the additional QALYs were 15,656 for 40% opportunistic, 31,161 for 80% opportunistic, 31,506 for 80% organised, 31,547 for 60% organised with 20% opportunistic, and 35,179 for 40% organised with 40% annual opportunistic screening.
The expected cost for the target population was EUR 1,239 million for no screening. Compared with no screening the additional costs were EUR 398 million for 40% opportunistic, EUR 796 million for 80% opportunistic, EUR 391 million for 80% organised, EUR 492 million for 60% organised with 20% opportunistic, and EUR 971 million for 40% organised with 40% annual opportunistic screening.
The cost per QALY gained compared with no screening was EUR 25,418 for 40% opportunistic, EUR 25,541 for 80% opportunistic, EUR 12,424 for 80% organised, EUR 15,601 for 60% organised with 20% opportunistic, and EUR 27,599 for 40% organised with 40% annual opportunistic screening.
Varying the sensitivity of opportunistic relative to organised screening caused the cost per QALY gained to vary from EUR 24,467 to EUR 26,700 for 80% opportunistic screening.