In light of the literature review, there are uncertainties concerning the indications for TUMT, especially about the clinical baseline parameters capable of predicting a good response to treatment. However, TUMT appears to be attractive for patients with a medical treatment failure or with contraindications for TURP. In this context, results are required from clinical studies with the new 30-minute high-energy TUMT protocol to provide evidence for the safety and efficacy of the procedure, particularly in terms of long-term outcome and identification of predictive baseline clinical parameters.