- One randomised trial was reviewed that met inclusion and exclusion criteria.
- The trial combined children with appendicitis from the age of 12 years with adults to the age of 48 years.
- This study found ceftriaxone, a cephalosporin, to be equally effective as a triple regimen of ampicillin, metronidazole plus gentamycin in the prophylaxis for postoperative sepsis.