This report indicates that nurse insertion of Hickman lines in the majority of adult cancer patients at Christie Hospital NHS Trust is both safe and effective. However, there are a select group of patients for whom image-guided insertion may be preferred. The results reveal that skills and expertise can be transferred from trainer to trainee through a relatively short but intensive training course. From the patient satisfaction evidence available, it is evident that patients support nurse insertion. Nurse insertions can free up clinical resources in a safe and effective manner at a time of unprecedented pressure within the NHS.