On the basis of the available literature, APAP shows promise but should be used with caution until further studies establish its effectiveness and cost-effectiveness. Observational studies show that there is a potential use for APAP for the diagnosis of OSA, although its efficacy in auto-titration (unattended adjustment of pressure) has not been established. Further validation is needed from studies with stronger methodology.
For the treatment of OSA, studies show that APAP uses a lower treatment pressure than CPAP. However, clinical outcomes with APAP are no better than those with CPAP, and it is uncertain whether there is better compliance with APAP. Potential safety issues for patients suffering from cardiac, pulmonary, and other medical conditions arise if APAP is used in settings without prompt access to technical support.