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A systematic review of the effectiveness and cost-effectiveness of neuroimaging assessments used to visualise the seizure focus in people with refractory epilepsy being considered for surgery |
Whiting P, Gupta R, Burch J, Mujica Mota R E, Wright K, Marson A, Weishmann U, Haycox A, Kleijnen J, Forbes C |
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Citation Whiting P, Gupta R, Burch J, Mujica Mota R E, Wright K, Marson A, Weishmann U, Haycox A, Kleijnen J, Forbes C. A systematic review of the effectiveness and cost-effectiveness of neuroimaging assessments used to visualise the seizure focus in people with refractory epilepsy being considered for surgery. Health Technology Assessment 2006; 10(4): 1-250 Authors' objectives <p>The aim of this report is to review the effectiveness and/or accuracy, cost-effectiveness, and predictive value of neuroimaging of the cerebral cortex to visualise the seizure focus in people with refractory epilepsy being considered for surgery.</p>
Authors' conclusions Due to the limitations of the included studies, the results of this review do little to inform clinical practice, with insufficient evidence regarding effectiveness and cost-effectiveness of imaging techniques in the work-up for epilepsy surgery. Given the inadequacy of existing data, there is a pressing need for studies investigating the utility of imaging techniques in the work up for epilepsy surgery. The most reliable method to achieve this is the RCT, which could examine the single tests or combinations of tests on patient outcome. The authors suggest that it is important that clinicians, patient groups, policy makers and healthcare/research funders meet and debate the most appropriate way to investigate these technologies.
INAHTA brief and checklist Indexing Status Subject indexing assigned by CRD MeSH Costs and Cost Analysis; Diagnostic Imaging; Epilepsy /surgery; Seizures /diagnosis Language Published English Country of organisation England English summary An English language summary is available. Address for correspondence NETSCC, Health Technology Assessment, Alpha House, University of Southampton Science Park, Southampton, SO16 7NS UK Tel: +44 23 8059 5586 Email: hta@hta.ac.uk AccessionNumber 32006000202 Date bibliographic record published 08/03/2006 Date abstract record published 08/03/2006 |
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