Citation Alvarez S, Rueda JR. Evaluacion de la efectividad de la deteccion intraoperatoria del ganglio centinela en tumores solidos. [Assessment of the effectiveness of the intraoperative detection of the sentry ganglion in solid tumours] Vitoria-Gasteiz: Basque Office for Health Technology Assessment (OSTEBA). D-06-01. 2006 Authors' objectives <p>Assess the effectiveness and reliability of the intraoperative detection of the sentry ganglion, and the extirpation or otherwise of the ganglion in accordance with the test results, in the treatment of tumours of the breast, vulva and penis as well as of melanomas.</p> Authors' conclusions In localised breast cancer, compared to the axillary lymphadenectomy option, which is currently the most habitual practice in our health services, the technical efficacy of the sentry ganglion technique is of an acceptable level for the detection of ganglion metastasis. This seems to be a reliable technique with regard to its repercussions on the survival of affected women and to the reoccurrence rate, in view of the fact that today, the immense majority of women with localised breast cancer are treated with a systemic treatment, be this with chemotherapy or tamoxifen. Compared to the axillary lymphadenectomy option, the sentry ganglion technique involves less risk of secondary effects. With regard to localised melanoma, for those health services that do not carry out routine regional lymphadenectomies, the sentry ganglion technique may be used to detect ganglion tumour alteration, which would benefit from a regional lymphadenectomy, in view of the fact that there are no systemic melanoma treatments of proven effectiveness. In those health services that perform routine regional lymphadenectomies, the sentry ganglion technique may be used to avoid unnecessary lymphadenectomies and also to detect unexpected drainage or ganglions in transit. In localised cancers of the vulva and localised cancers of the penis, the technique appears to the quite reliable, and seems to represent, therefore, a promising technique capable of avoiding a large number of unnecessary radical lymphadenectomies. Indexing Status Subject indexing assigned by CRD MeSH Biopsy; Lymphatic Metastasis /diagnosis; Monitoring, Intraoperative; Neoplasm Metastasis /diagnosis; Neoplasms /surgery; Sentinel Lymph Node Biopsy Language Published Spanish Country of organisation Spain English summary An English language summary is available. English Summary English summary available Address for correspondence Calle Donostia 1, ES-01010 Vitoria-Gasteiz, Spain, Tel: +34 9 45 01 9250, Fax: +34 9 45 01 9280 Email: jasua-osteba@ej-gv.es AccessionNumber 32006001533 Date bibliographic record published 17/11/2006 Date abstract record published 17/11/2006 |