The cost-effectiveness studies suggest that MRI for breast cancer screening could be costeffective, depending on the willingness to pay and the value attributed to one QALY. Overall, MRI has a higher sensitivity for breast cancer screening compared to mammography. In addition, the number of cancers detected by MRI alone was higher than that detected by mammography alone, although MRI also missed some cancers. These results indicate that some breast cancers would have been missed with mammography screening alone and the addition of MRI resulted in more cancers being detected. High-risk women, such as those with BRCA1/2 mutations, those having a first-degree relative with a mutation, or those with a strong family history of breast cancer, seem to benefit most from the addition of MRI to the screening modality.