Chronic pain, or pain lasting longer than 3 months or beyond the time of expected tissue healing, is thought to affect 2% to 40% of the adult population. Chronic nonmalignant pain includes central pain, fibromyalgia, ischemic pain, neuropathic pain, orofacial pain, phantom/stump pain, postherpetic neuralgia, and complex regional pain syndrome (CRPS). CRPS is a severe chronic pain condition that most often develops following trauma. Most chronic pain disorders respond best to a combination of treatment modalities or a multidisciplinary plan including physical therapy, drug therapy, sympathetic nerve block, spinal cord stimulation, and intrathecal drug pumps to deliver opioids and local anesthetic agents via the spinal cord.