Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation CADTH. Continuous positive airway pressure compared with oral devices or lifestyle changes for the treatment of obstructive sleep apnea: a review of the clinical and cost-effectiveness. Ottawa: Canadian Agency for Drugs and Technologies in Health (CADTH). Rapid Response. 2014 Authors' conclusions In general, results from the controlled setting of RCTs and systematic reviews of RCTs found that CPAP lead to better efficacy than oral devices. This benefit may be offset by patient's higher compliance to oral devices which may result in similar real-life clinical effectiveness. CPAP may be more costly than oral devices or lifestyle advice, and oral devices may be a more cost-effective option in patients who are unable to adhere to CPAP. The small number of trials included in the report, the significant heterogeneity between the included trials for many outcomes, the difference in length of follow-up periods, and the potential difference in costs, treatment effect and adherence of various types of oral appliances caution the interpretation of the results. Indexing Status Subject indexing assigned by CRD MeSH Airway Resistance; Continuous Positive Airway Pressure; Lifestyle; Sleep Apnea Syndromes; Snorings; Weight Reduction Language Published English Country of organisation Canada English summary An English language summary is available. Address for correspondence Canadian Agency for Drugs and Technologies in Health (CADTH), 865 Carling Avenue, Suite 600, Ottawa, Ontario Canada, K1S 5S8 Email: requests@cadth.ca AccessionNumber 32016000158 Date abstract record published 28/01/2016 |