Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Malaysian Health Technology Assessment (MaHTAS). Platelet rich plasma for treatment of osteoarthritis. Putrajaya: Malaysian Health Technology Assessment (MaHTAS). Technology Review Report – 010/2013. 2013 Authors' objectives To assess the efficacy, safety and cost-effectiveness of platelet rich plasma for the treatment of osteoarthritis. Authors' conclusions Two systematic reviews, two randomised controlled trials and a non-randomised controlled trial were included in this review.
There was insufficient but good level of evidence to support the effectiveness of PRP for the treatment of osteoarthritis. The longest outcome data available was only for 24 months in a study and revealed that the median beneficial results was nine months. Most of the studies available were case series. Studies that have comparisons, used hyaluronic acid as control. In certain countries such as the United Kingdom, intra-articular hyaluronic acid injections are not recommended for the treatment of osteoarthritis.
The short term evidence showed that PRP may be beneficial for young (<50 years old) patients with early OA
and not overweight or obese. However, the evidence is limited. In terms of safety, no major complications were
reported in patients treated with PRP. INAHTA brief and checklist INAHTA brief and checklist Indexing Status Subject indexing assigned by CRD MeSH Humans; Osteoarthritis, Knee; Platelet-Rich Plasma Language Published English Country of organisation Malaysia English summary An English language summary is available. Address for correspondence Health Technology Assessment Section, Ministry of Health Malaysia, Federal Government Administrative Centre, Level 4, Block E1, Parcel E, 62590 Putrajaya Malaysia
Tel: +603 888 312 29 Email: htamalaysia@moh.gov.my AccessionNumber 32016000506 Date abstract record published 09/03/2016 |