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Chlorhexidine wash prior to clean surgical procedures |
Rahm C, Adlerberth I, Erichsen Andersson A, Freadrich K, Jivegård L, Kullgren A, Svanberg T, Wold A, Sjögren P |
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Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Rahm C, Adlerberth I, Erichsen Andersson A, Freadrich K, Jivegård L, Kullgren A, Svanberg T, Wold A, Sjögren P. Chlorhexidine wash prior to clean surgical procedures. Gothenburg: The Regional Health Technology Assessment Centre (HTA-centrum). HTA-rapport 2015:83. 2015 Authors' conclusions The question at issue was studied in seven RCTs and three cohort studies. Drawbacks of the included studies were that the time of follow-up was often short and only two cohort studies investigated implant infections, a more critical outcome than SSI in general. All included studies had some or major limitations regarding blinding, definition of outcomes, length of follow up and heterogeneity of patient populations. The current systematic review shows that preoperative CHX compared with placebo showering/bathing may be associated with little or no difference in SSI in patients undergoing "clean" surgery. For all other comparisons the certainty of evidence was very low. The confidence interval of the pooled effect estimate includes a negative effect and there is a need for further large studies. Indexing Status Subject indexing assigned by CRD MeSH Anti-Infective Agents, Local; Chlorhexidine; Humans Language Published English Country of organisation Sweden English summary An English language summary is available. Address for correspondence The Regional Health Technology Assessment Centre, Region Vastra Gotaland, HTA-centrum, Roda Straket 8, Sahlgrenska Universitetssjukhuset, 413 45 GOTHENBORG, Sweden Email: hta-centrum@vgregion.se AccessionNumber 32016000603 Date abstract record published 29/03/2016 |
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