Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation NIHR HSRIC. C3BS-CQR-1 (C-Cure) for heart failure secondary to ischaemic cardiomyopathy. Birmingham: NIHR Horizon Scanning Research&Intelligence Centre. Horizon Scanning Review. 2016 Authors' conclusions Heart failure is a common and disabling condition that affects the heart's ability to pump blood around the body. It is often caused by coronary heart disease (ischaemic heart disease), which happens when there is a build-up of fatty deposits in the blood vessels of the heart. These fatty deposits mean the heart muscle does not receive enough oxygen to work properly or they may completely block off a blood vessel leading to a heart attack (myocardial infarction), where a section of heart muscle dies completely.
Current treatments for heart failure aim to improve the symptoms of heart failure, improve the heart's pumping action, and prevent further myocardial infarctions. C3BS-CQR-1 is a new type of treatment that aims to repair and regenerate heart muscle. It is produced from the patient's own bone marrow cells and is injected directly into the damaged areas of heart muscle. It is currently being studied to see whether it improves the symptoms of heart failure and reduces the chance that a patient dies from their disease.
If C3BS-CQR-1 is licensed for use in the UK, it could offer a completely new treatment option that has the potential to repair damaged heart muscle in patients with heart failure. Indexing Status Subject indexing assigned by CRD MeSH Cardiomyopathies; Chronic Disease; Heart Failure; Humans; Myocardial Ischemia Language Published English Country of organisation England English summary An English language summary is available. Address for correspondence NIHR Horizon Scanning Research&Intelligence Centre, University of Birmingham, Institute of Applied Health Research, Public Health building, Edgbaston, Birmingham B15 2TT
Tel: 0121 414 9077 Email: nihrhsc@contacts.bham.ac.uk AccessionNumber 32016000749 Date abstract record published 14/06/2016 |