Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation NIHR HSRIC. Naldemedine for opioid-induced constipation in adults. Birmingham: NIHR Horizon Scanning Research&Intelligence Centre. Horizon Scanning Review. 2016 Authors' conclusions Opioids are a class of drugs that are commonly prescribed for pain. Constipation is a side effect that affects nearly all patients taking opioid treatment. There has been an increase in the use of opioids to treat chronic pain in recent years. Current treatment for opioid-induced constipation often involves laxatives. But, it has been estimated that 50–80% of people taking laxatives for opioid-induced constipation get only a limited improvement in symptoms.
Naldemedine is a new drug for the treatment of opioid-induced constipation in adults that is taken as a tablet once a day. If it is licensed for use in the UK, naldemedine may offer an additional treatment option for adults with this debilitating condition. Indexing Status Subject indexing assigned by CRD MeSH Adult; Analgesics, Opioid; Constipation; Humans; Narcotic Antagonists Language Published English Country of organisation England English summary An English language summary is available. Address for correspondence NIHR Horizon Scanning Research&Intelligence Centre, University of Birmingham, Institute of Applied Health Research, Public Health building, Edgbaston, Birmingham B15 2TT
Tel: 0121 414 9077 Email: nihrhsc@contacts.bham.ac.uk AccessionNumber 32016000815 Date abstract record published 22/06/2016 |