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The use of fibrin sealant during non-emergency surgery: a systematic review of evidence of benefits and harms |
Edwards S J, Crawford F, van Velthoven M H, Berardi A, Osei-Assibey G, Bacelar M, Salih F & Wakefield V |
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Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Edwards S J, Crawford F, van Velthoven M H, Berardi A, Osei-Assibey G, Bacelar M, Salih F & Wakefield V. The use of fibrin sealant during non-emergency surgery: a systematic review of evidence of benefits and harms. Health Technology Assessment 2017; 20(94) Authors' objectives To systematically review the evidence on the benefits and harms of fibrin sealants in non-emergency surgery in adults. Authors' conclusions The effectiveness of fibrin sealants does not appear to vary according to surgical procedures with regard to reducing the risk of seroma or haematoma. Surgeons should note the potential risk of gas embolism if spray application of fibrin sealants is used and not to exceed the recommended pressure and spraying distance. Future research should be carried out in surgery specialties for which only limited data were found, including neurological, gynaecological, oral and maxillofacial, urology, colorectal and orthopaedics surgery (for any outcome); breast surgery and upper gastrointestinal (development of haematoma); and cardiothoracic heart or lung surgery (reoperation rates). In addition, studies need to use adequate sample sizes, to blind participants and outcome assessors, and to follow reporting guidelines. Indexing Status Subject indexing assigned by CRD MeSH Fibrin Tissue Adhesive; Humans; Tissue Adhesives Language Published English Country of organisation England English summary An English language summary is available. Address for correspondence NETSCC, Health Technology Assessment, Alpha House, University of Southampton Science Park, Southampton, SO16 7NS UK Tel: +44 23 8059 5586 Email: hta@hta.ac.uk AccessionNumber 32017000089 Date abstract record published 10/01/2017 |
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