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PET-NECK: a multicentre randomised Phase III non-inferiority trial comparing a positron emission tomography computerised tomography-guided watch-and-wait policy with planned neck dissection in the management of locally advanced (N2/N3) nodal metastases in patients with squamous cell head and neck cancer |
Mehanna H, McConkey CC, Rahman JK, Wong W, Smith AF, Nutting C, Hartley AG, Hall P, Hulme C, Patel DK, Zeidler SV v, Robinson M, Sanghera B, Fresco L & Dunn JA |
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Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Mehanna H, McConkey CC, Rahman JK, Wong W, Smith AF, Nutting C, Hartley AG, Hall P, Hulme C, Patel DK, Zeidler SV v, Robinson M, Sanghera B, Fresco L & Dunn JA. PET-NECK: a multicentre randomised Phase III non-inferiority trial comparing a positron emission tomography computerised tomography-guided watch-and-wait policy with planned neck dissection in the management of locally advanced (N2/N3) nodal metastases in patients with squamous cell head and neck cancer. Health Technology Assessment 2017; 21(17) Authors' objectives To determine the efficacy and cost-effectiveness of PET–CT-guided surveillance, compared with planned ND, in a multicentre, prospective, randomised setting. Authors' conclusions PET–CT-guided active surveillance showed similar survival outcomes to ND but resulted in considerably fewer NDs, fewer complications and lower costs, supporting its use in routine practice. Indexing Status Subject indexing assigned by CRD MeSH Epithelial Cells; Head and Neck Neoplasms; Humans; Neck Dissection; Positron Emission Tomography Computed Tomography Language Published English Country of organisation England English summary An English language summary is available. Address for correspondence NETSCC, Health Technology Assessment, Alpha House, University of Southampton Science Park, Southampton, SO16 7NS UK Tel: +44 23 8059 5586 Email: hta@hta.ac.uk AccessionNumber 32017000199 Date abstract record published 21/04/2017 |
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