Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Erdös J, Ibargoyen Roteta N, Gutiérrez Ibarluzea I. Repetitive transcranial magnetic stimulation for treatment-resistant major depression. Vienna: Ludwig Boltzmann Institut fuer Health Technology Assessment (LBIHTA). Decision Support Document. 2017 Authors' objectives Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive neurostimulation technique indicated for patients with treatment-resistant unipolar major depression (TRD). The stimulation is carried out by a coil that is placed on the scalp and delivers brief magnetic pulses. We evaluated the efficacy and safety of high-frequency stimulation to the left dorsolateral prefrontal cortex compared to sham stimulation, as well as to electroconvulsive therapy (ECT). Authors' conclusions The current evidence indicates that rTMS is more effective than and as safe as sham, but it is not sufficient to prove that it is as effective and safe as ECT. Due to the low quality of evidence we recommend rTMS for patients with TRD with restrictions. Indexing Status Subject indexing assigned by CRD MeSH Depression; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Humans; Transcranial Magnetic Stimulation Language Published English Country of organisation Austria English summary An English language summary is available. Address for correspondence Ludwig Boltzmann Institute fuer Health Technology Assessment (LBI-HTA), Garnisongasse 7 rechte Stiege Mezzanin (Top 20), 1090 Vienna, Austria. Tel: +43 1 236 8119 - 0 Fax: +43 1 236 8119 - 99 AccessionNumber 32017000337 Date abstract record published 01/08/2017 |