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Observational study to estimate the changes in the effectiveness of bacillus Calmette Guerin (BCG) vaccination with time since vaccination for preventing tuberculosis in the UK |
Mangtani P, Nguipdop-Djomo P, Keogh R H, Trinder L, Smith P G, Fine P E, Sterne J, Abubakar I, Vynnycky E, Watson J, Elliman D, Lipman M & Rodrigues L C |
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Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Mangtani P, Nguipdop-Djomo P, Keogh R H, Trinder L, Smith P G, Fine P E, Sterne J, Abubakar I, Vynnycky E, Watson J, Elliman D, Lipman M & Rodrigues L C. Observational study to estimate the changes in the effectiveness of bacillus Calmette Guerin (BCG) vaccination with time since vaccination for preventing tuberculosis in the UK. Health Technology Assessment 2017; 21(39) Authors' objectives To assess the duration of protection of infant and school-age BCG vaccination against TB in the UK. Authors' conclusions Infant BCG vaccination in a population at high risk for TB was shown to provide protection for at least 10 years, whereas in the white population school-age vaccination was shown to provide protection for at least 20 years. This evidence may inform TB vaccination programmes (e.g. the timing of administration of improved TB vaccines, if they become available) and cost-effectiveness studies. Methods to deal with missing record data in the infant study could be explored, including the use of scar reading. Indexing Status Subject indexing assigned by CRD MeSH Antibiotic Prophylaxis; Bacillus; Humans; Mycobacterium bovis; Tuberculosis; Vaccination Language Published English Country of organisation England English summary An English language summary is available. Address for correspondence NETSCC, Health Technology Assessment, Alpha House, University of Southampton Science Park, Southampton, SO16 7NS UK Tel: +44 23 8059 5586 Email: hta@hta.ac.uk AccessionNumber 32017000383 Date abstract record published 19/09/2017 |
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