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Neodymium-doped yttrium aluminium garnet laser treatment for onychomycosis |
HAYES, Inc |
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Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation HAYES, Inc. Neodymium-doped yttrium aluminium garnet laser treatment for onychomycosis. Lansdale: HAYES, Inc. Healthcare Technology Brief Publication. 2017 Authors' conclusions Onychomycosis is a fungal infection of the nail. Onychomycosis can cause discomfort, pain, and disfigurement leading to serious physical and occupational limitations. Onychomycosis is a deepseated,
recalcitrant condition with a 40% to 70% recurrence rate, which includes either relapse or reinfection. Oral antifungals are the standard of care because topical application has limited effectiveness due to the difficulty of nail penetration. However, systemic antifungals are associated with hepatic toxicity and drug interactions. Additionally, topical or oral antifungal treatment must be maintained for several months for maximal effectiveness, and patient compliance is a common issue.
Description of Technology: Neodymium-doped yttrium aluminium garnet (Nd:YAG) lasers typically have a wavelength of 1064 nanometers and a variety of pulse durations to impact the power of laser treatment, including long-pulsed (milliseconds), short-pulsed (microseconds), and Qswitched (nanoseconds).
Patient Population: Laser therapy is indicated for patients with toenail or fingernail onychomycosis.
Clinical Alternatives: Onychomycosis may be treated with oral (e.g., terbinafine, itraconazole, fluconazole, posaconazole, griseofulvin) or topical (e.g., ciclopirox olamine, efinaconazole, amorolfine, bifonazole, tioconazole, tavaborate) antifungal agents or nonpharmacologic treatments (e.g., laser treatment, photodynamic therapy, nail debridement, nail evulsion). Pharmacologic and nonpharmacologic treatments may also be used in combination. Indexing Status Subject indexing assigned by CRD MeSH Humans; Lasers, Solid-State; Neodymium; Onychomycosis; Phosphatidylethanolamines Language Published English Country of organisation United States English summary An English language summary is available. Address for correspondence HAYES, Inc., 157 S. Broad Street, Suite 200, Lansdale, PA 19446, USA. Tel: 215 855 0615; Fax: 215 855 5218 Email: hayesinfo@hayesinc.com AccessionNumber 32017000392 Date abstract record published 20/09/2017 |
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