How are the functional results after early and late THA after acetabular fracture?
How is implant survival of early and late THA after acetabular fracture?
What are the problems and complications seen in early and late THA after acetabular fracture?
Searches in MEDLINE, EMBASE and the Cochrane Library.
Search fields are [total hip arthroplasty] AND [acetabular fracture] and all terms comparable to these fields, like prosthesis, replacement and acetabulum.
There will be no restrictions to time in the past. The search will be re-run just before final analysis to check for new publications.
The language is restricted to English and German
Types of study to be included
All clinical (randonized) trials and observational studies are eligible for inclusion.
Excluded are case reports, descriptions of surgical techniques and reviews
Condition or domain being studied
Total hip arthroplasty as primary or secondary treatment for an acetabular fracture.
Inclusion: Patients of all ages receiving a total hip arthroplasty as primary or secondary treatment for/after an acetabular fracture.
Exclusion: Patients with an acetabular fracture as a result of a primary revision total hip arthroplasty.
The intervention is the implantation of a total hip arthroplasty in all patients who sustained an acetabular fracture.
The review will compare patients who receive the THA as the early, primary treatment of the fracture with patients who receive the THA as late, secondary treatment for posttraumatic arhtritis after an acetabular fracture
The quality of individual studies will be assessed using the GRADE methodology by two independent reviewers. For discrepancies in assessment a third reviewer will be consulted to obtain consensus.
Strategy for data synthesis
We will do a data synthesis at the aggregate patient data. Most results will be narrative, but where possible, a quantitative synthesis will be performed. Based on our preliminary searches we expect few possibilities for meta-analysis. In reporting the data will will take the quality assessment using GRADE into account.
Analysis of subgroups or subsets
If data available are robust enough we hope to do a subgroup analysis on patients receiving a late total hip, because of posttraumatic arthritis.
The subgroups to be identified are whether initial treatment for the fracture was conservative or operative.
In addition to publishing the review, we will aim to present the results at (inter)national conferences
Contact details for further information
Dirk Jan Moojen
St. Michael's Hospital
Division of Orthopaedics
30 Bond Street
M5B 1W8 Canada
Organisational affiliation of the review
St. Michael's Hospital, Toronto, ON
Dr Dirk Jan Moojen, Division of Orthopaedics, St. Michael's Hospital, Toronto, ON, Canada Dr Paul Kuzyk, Division of Orthopaedics, Mount Sinai Hospital, Toronto, ON, Canada Dr Emil Schemitsch, Division of Orthopaedics, St. Michael's Hospital, Toronto, ON, Canada Mr Michel Saccone, University of Toronto
Details of any existing review of the same topic by the same authors
Formal screening of search results against eligibility criteria
Risk of bias (quality) assessment
PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites.