PROSPERO International prospective register of systematic reviews
 
Long-term high protein versus low protein dietary regimens and their outcome on cardiovascular and metabolic risk factors: a systematic review and meta-analysis
Lukas Schwingshackl
 
Citation
Lukas Schwingshackl. Long-term high protein versus low protein dietary regimens and their outcome on cardiovascular and metabolic risk factors: a systematic review and meta-analysis. PROSPERO 2012:CRD42012002791 Available from http://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42012002791
Review question(s)

Long-term effects of high vs. low protein diets on cardiovascular risk factors?

Long-term effects of high vs. low protein diets on renal function?

Searches

MEDLINE (no restriction to language or publication period).

EMBASE (no restriction to language or publication period).

Cochrane Central Register of Controlled Trials (CENTRAL) (no restriction to language or publication period).

Types of study to be included

Randomized controlled trials.

Condition or domain being studied

CVD risk factors (i.e. blood lipida, markers of glucose metabolism, blood pressure, anthropometric markers)

Participants/ population

Overweight, obese, T2D, abnormal glucose metabolism.

Intervention(s), exposure(s)

high protein diets >25% of total energy content and low in fat 30% of total energy content.

vs.

low protein diets 10-20% of total energy content and low in fat 30% of total energy content.

long-term effects (>=12 months) on CVD risk factors.

Comparator(s)/ control

Low protein diets 10-20% of total energy content and low in fat 30% of total energy content.

Outcome(s)

Primary outcomes

CVD risk factors.

Secondary outcomes

Weight, fat mass.

Risk of bias (quality) assessment

Jadad Score

Strategy for data synthesis

Post values and mean differences.

Unstandardized random effect modell.

Weighted mean differences.

Analysis of subgroups or subsets

Subgroup analysis on participants without T2D.

Contact details for further information

Lukas Schwingshackl

Althanstrae 14

1090 Vienna

Department of Nutritional Sciences

Faculty of Life Sciences

University of Vienna

lukas.schwingshackl@umit.at

Organisational affiliation of the review

Althanstrae 14 1090 Vienna Department of Nutritional Sciences Faculty of Life Sciences University of Vienna

Review team

Mr Lukas Schwingshackl, Department of Nutritional Sciences Faculty of Life Sciences University of Vienna

Collaborators

Professor Georg Hoffmann, Department of Nutritional Sciences Faculty of Life Sciences University of Vienna

Anticipated or actual start date

01 August 2012

Anticipated completion date

14 September 2012

Funding sources/sponsors

None

Conflicts of interest

None known

Language

English

Country

Austria

Subject index terms status

Subject indexing assigned by CRD

Subject index terms

Cardiovascular Diseases; Diet, Fat-Restricted; Dietary Proteins; Humans; Risk Factors

Date of registration in PROSPERO

10 August 2012

Date of publication of this revision

28 August 2012

Stage of review at time of this submission Started   Completed
Preliminary searches Yes  
Piloting of the study selection process  
Formal screening of search results against eligibility criteria  
Data extraction  
Risk of bias (quality) assessment  
Data analysis  
Prospective meta-analysis  
 
PROSPERO
This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites.
 
 
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Revision Notes
Revision History
Aug 10 2012 9:57AM