PROSPERO International prospective register of systematic reviews
Effectiveness of music therapy: a summary of systematic reviews based on randomized controlled trials of music interventions
Hiroharu Kamioka, Kiichiro Tsutani, Monoru Yamada, Hyuntae Park, Hiroyasu Okuizumi, Koki Tsuruoka, Takuya Honda, Shinpei Okada, Sang-Jun Park, Jun Kitayuguchi, Takafumi Abe, Shuichi Handa, Takuya Oshio, Yoshiteru Mutoh
Hiroharu Kamioka, Kiichiro Tsutani, Monoru Yamada, Hyuntae Park, Hiroyasu Okuizumi, Koki Tsuruoka, Takuya Honda, Shinpei Okada, Sang-Jun Park, Jun Kitayuguchi, Takafumi Abe, Shuichi Handa, Takuya Oshio, Yoshiteru Mutoh. Effectiveness of music therapy: a summary of systematic reviews based on randomized controlled trials of music interventions.
Available from http://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42012002950
The objective of this review is to summarize evidence for the effectiveness of music therapy and to assess the quality of systematic reviews based on randomized controlled trials of these therapies.
We search the following databases from 1995 up to October 1, 2012: MEDLINE via PubMed, CINAHL, Web of Science, Ichushi Web (in Japanese), the Global Health Library (GHL), and the Western Pacific Region Index Medicus (WPRIM). The International Committee of Medical Journal Editors (ICMJE) recommended uniform requirements for manuscripts submitted to biomedical journals in 1993. We select articles published (that included a protocol) since in 1995, because it appears hat the ICMJE recommendation had been adopted by the relevant researchers and had strengthened the quality of reports.
We also search the Cochrane Database of Systematic Reviews (Cochrane Reviews), the Database of Abstracts of Reviews of Effects (Other Reviews), the Cochrane Central Register of Controlled Trials (Clinical Trials or CENTRAL), the Cochrane Methodology Register (Methods Studies), the Health Technology Assessment Database (Technology Assessments), the NHS Economic Evaluation Database (Economic Evaluations), About The Cochrane Collaboration databases (Cochrane Groups) and Campbell Systematic Reviews (the Campbell Collaboration), the All Cochrane all up to October 1, 2012.
All searches are performed by two specific searchers (hospital librarians) who are qualified in medical information handling, and who are sophisticated in searches of clinical trials.
The special search strategies contain the elements and terms for MEDLINE, CINAHL, Web of Science, Ichushi Web, GHL, WPRIM, and All Cochrane databases. Only keywords about intervention aree used for the searches. First, titles and abstracts of identified published articles are reviewed in order to determine the relevance of the articles. Next, references in relevant studies and identified SRs are screened.
We search the International Clinical Trials Registry Platform (ICTRP), the International Prospective Register of Systematic Review (PROSPERO), the Clinical Trials.gov, and the University Hospital Medical Information Network-Clinical Trials Registry (UMIN-CTR) up to October 1, 2012.
ICTRP in the WHO Registry Network meet specific criteria for content, quality and validity, accessibility, unique identification, technical capacity and administration. Primary registries meet the requirements of the ICMJE. Clinical Trials.gov is a registry of federally and privately supported clinical trials conducted in the United States (US) and around the world. UMIN-CTR is registries of clinical trials conducted in Japan and around the world.
Handsearching, reference checking ,and other
We handsearch abstracts published in recreation activities and relevant journals in Japan. We checked the references of included studies for further relevant literature.
Types of study to be included
Studies were eligible if they were systematic reviews (with or without a meta-analysis) based on randomized controlled trials.
Condition or domain being studied
We focus on all cure and rehabilitation effects with the International Classification of Diseases-10 (ICD-10).
There is no restriction on patients.
Studies include at least one treatment group in which music therapy is applied. The definition of the music therapy is difficult, but, in this study, any kind of music therapy (not only music appreciation but also musical instrument performance, singing, and so on) is permitted and defined as intervention. Studies have to include information on use of medication, alternative therapies, and lifestyle changes, and these have to be comparable among groups.
As control, pre-planned stratified analyses are: a) trials comparing music therapies with no treatment or waiting list controls, b) trials comparing different types of other methods (e.g., physical therapy, occupational therapy, and so on), c) trials comparing music therapies with other different intervention(s).
We focuse on all cure and rehabilitation effects with the International Classification of Diseases-10 (ICD-10).
There is no restriction on secondary outcomes.
Data extraction, (selection and coding)
In order to make the final selection of studies for the review, all criteria are applied independently by four authors (e.g., TH, JK, SP, TA) to the full text of articles that have passed the first eligibility screening . Disagreements and uncertainties are resolved by discussion with other author (e.g. HK, KT, YM).
Studies are selected when (i) the design is a SR based on RCTs and (ii) one of the interventions is a form of music therapy. Protocol without results is excluded and we include only completely finished studies. Cure and rehabilitation effects are used as a primary outcome measure. Trials that are excluded are presented with reasons for exclusion.
Risk of bias (quality) assessment
In order to ensure that variation is not caused by systematic errors in the study design or execution, nine review authors (HP, MY, HO, SO, SP, TH, SH, JK, and HK) independently assess the quality of articles. A full quality appraisal of these papers is made using the combined tool based on the AMSTAR checklist developed to assess the methodological quality of SRs.
Each item is scored as ‘present’ (Yes), ‘absent’ (No), ‘unclear or inadequately described’ (Can’t answer), or ‘Not applicable’ (n/a). Depending on the study design, some items are not applicable. The “n/a” is excluded from calculation for quality assessment. We display percentage of present description on all 11-check items for quality assessment of articles. Each item is then assigned in view point of a risk of poor methodology and/or bias based on the following cut-offs: good description (80-100%), poor description (50-79%), very poor description (0-49%).
Disagreements and uncertainties are resolved by discussion with other authors (e.g. TK and HK). Inter-rater reliability was calculated on a dichotomous scale using percentage agreement and Cohen’s kappa coefficient (k).
Strategy for data synthesis
The results of each meta-analysis are planned to express, when possible, as relative risk (RR) with corresponding 95 percent confidence intervals (95%CI) for dichotomous data, and as standardized or weighted mean differences (SMD) with 95%CI for continuous data.
Analysis of subgroups or subsets
Contact details for further information
Sakuragaoka 1-1-1, Setagayaku, Tokyo, Japan
Organisational affiliation of the review
Faculty of Regional Environment Science,Tokyo University of Agriculture
Professor Hiroharu Kamioka, Faculty of Regional Environment Science,Tokyo University of Agriculture Professor Kiichiro Tsutani, Department of Drug Policy and Management, Graduate School of Pharmaceutical Sciences, The University of Tokyo Dr Monoru Yamada, Human Health Sciences, Kyoto University Graduate School of Medicine Dr Hyuntae Park, Department of Functioning Activation, National Center for Geriatrics and Gerontology Dr Hiroyasu Okuizumi, Mimaki Onsen (Spa) Clinic, Tomi City Dr Koki Tsuruoka, Tsurukame Clinic Mr Takuya Honda, Fellow of the Japanese Society for the Promotion of Science Mr Shinpei Okada, Physical Education and Medicine Research Foundation Mr Sang-Jun Park, Physical Education and Medicine Research Foundation Mr Jun Kitayuguchi, Physical Education and Medicine Research Center Unnan Mr Takafumi Abe, Physical Education and Medicine Research Center Unnan Shuichi Handa, Mimaki Onsen (Spa) Clinic, Tomi City Mr Takuya Oshio, Social Welfare Service Corporation CARE-PORT MIMAKI Professor Yoshiteru Mutoh, Todai Policy Alternatives Research Institute, The University of Tokyo
Ms Satoko Sayama, Ms Mari Makishi, Ms Aya Maruyama, Ms Rie Higashino, Ms Yoko Ikezaki,
Details of any existing review of the same topic by the same authors
Anticipated or actual start date
14 September 2012
Anticipated completion date
31 January 2013
This study is supported by the Health and Labour Sciences Research Grants (representative; Prof. Tsutani K) from the Japanese Ministry of Health, Labour and Welfare of Japan in 2012.
Conflicts of interest
Subject index terms status
Subject indexing assigned by CRD
Subject index terms
Humans; Music Therapy
Date of registration in PROSPERO
14 September 2012
Date of publication of this revision
02 October 2012
Stage of review at time of this submission
Piloting of the study selection process
Formal screening of search results against eligibility criteria
Risk of bias (quality) assessment
PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites.