Does Parkinson's disease associate with a higher postoperative morbidity and mortality after abdominal surgery?
Does Parkinson's disease affect the length of hospital and/or ICU stay after abdominal surgery?
Searches
The PubMed, EMBASE and Cochrane bibliographic libraries will be used to retrieve all publications referring to Parkinson's disease without any language, publication period, or other restrictions.
- Experimental studies involving animals, basic science in vivo/in vitro
- Purely translational studies (human tissue but experimental without long term outcomes)
- Published conference abstracts
Condition or domain being studied
Parkinson's disease
Participants/ population
Inclusion criteria
- Parkinson's disease
- Patients undergoing abdominal surgery
Exclusion criteria
- Patients undergoing other types of surgery than abdominal surgery (also excluding neurosurgery)
Intervention(s), exposure(s)
Inclusion criteria:
- Patients undergoing abdominal surgery
Exclusion criteria
- Patients undergoing other types of surgery than abdominal surgery (also excluding neurosurgery)
Comparator(s)/ control
Patients with parkinson disease who undergo abdominal surgery will be compared to patients without this condition who also undergo abdominal surgery.
Outcome(s)
Primary outcomes
1. Postoperative morbidity
2. Postoperative mortality
Secondary outcomes
1. LOH stay
2. Length of ICU stay
Risk of bias (quality) assessment
The Oxford and GRADE systems will be used to assess the quality of the individual studies.
Strategy for data synthesis
Both aggregate and at the level of individual manuscripts will be used for narrative as well as quantitative synthesis.
Analysis of subgroups or subsets
- UGI surgery
- CRC surgery
- HPB surgery
- General surgery
- Others
Contact details for further information
Lukasz Filip Grochola
Klinik fuer Viszeral- und Transplantationschirurgie
Universitaetsspital Zuerich
Raemistrasse 100
8091 Zuerich
Switzerland
lukaszfilip.grochola@usz.ch
Organisational affiliation of the review
Klinik fuer Viszeral- und Transplantationschirurgie, University Hospital of Zurich
http://www.vis.usz.ch/Seiten/default.aspx
Review team
Dr Lukasz Filip Grochola, Klinik fuer Viszeral- und Transplantationschirurgie, University Hospital of Zurich Dr Dimitri Raptis, Klinik fuer Viszeral- und Transplantationschirurgie, University Hospital of Zurich Dr Stefan Breitenstein, Klinik fuer Viszeral- und Transplantationschirurgie, University Hospital of Zurich
Details of any existing review of the same topic by the same authors
Formal screening of search results against eligibility criteria
Data extraction
Risk of bias (quality) assessment
Data analysis
Prospective meta-analysis
PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites.
