Thirty-seven trials were included: 23 assessed smoking interventions, 6 assessed alcohol-related interventions, 10 assessed dietary interventions and 6 assessed exercise-related interventions; 23 were suitable for meta-analysis (total n=16,385).
Effectiveness of smoking cessation advice: provision of either brief or intensive advice significantly increases the odds of stopping smoking compared to no advice, odds ratio (OR) 1.32 (95% confidence interval, CI: 1.18, 1.48), with the odds being higher for intensive advice rather than brief advice (1.46 versus 1.27). The numbers-needed-to-treat are therefore, 35 for advice, 50 for brief advice, and 25 for intensive advice. However, in studies directly comparing brief with intensive advice, there is no significant difference between brief and intensive advice (OR=1.07, 95% CI: 0.88, 1.29).
Alcohol consumption: half of the trials found that consumption was significantly reduced when advice was provided, but this was not felt to provide conclusive evidence for or against the effectiveness of this intervention.
Dietary behaviour: the results of the trials were mixed, making it difficult to draw conclusions.
Exercise: again, the results of the primary studies made it difficult to determine the effectiveness of exercise, although a range of parameters relevant to cardiovascular disease risk (e.g. lipid levels, blood-pressure or weight reduction) were affected by provision of advice relating to exercise.