Nineteen studies (at least 15,964 participants) were included in the analysis: 14 RCTs, one controlled trial, one quasi-experimental trial and three described as follow-up studies. In terms of methodological quality, one study scored 9 points, five studies scored 8 points, nine studies scored 7 points and three studies scored 6 points.
Prevalence of Overweight and Obesity (seven studies): Overall, school-based obesity interventions were more effective in decreasing the number of participants who became overweight or obese than control groups (OR 0.74, 95% CI 0.60 to 0.92; seven studies). Studies with a duration of less than six months reported no significant differences between groups. Interventions that lasted one to two years reported a significantly lower likelihood of participants being overweight or obese compared to control (OR 0.81, 95% CI 0.68 to 0.92; three studies), as did interventions that lasted more than two years (OR 0.59, 95% CI 0.37 to 0.94; two studies). There were no statistically significant differences between groups for long-term follow up (three studies). There was evidence of significant statistical heterogeneity for the analysis of studies of interventions of more than two years duration (I2=83%).
BMI (11 studies): Overall there were no statistically significant differences between school-based intervention programmes and controls for BMI (11 studies). There was a significantly greater decrease in BMI with school-based interventions of between one and two years duration (WMD -0.10, 95% CI -0.14 to -0.06; two studies) compared to control. No significant differences between groups were found for studies with an intervention duration of less than six months to one year (six studies) and for studies with an intervention duration of more than two years (two studies). School-based intervention programmes reported a significantly greater reduction in BMI compared to control for long-term follow-up of between one and 10 years (WMD -0.42, 95% CI -0.69 to -0.14; two studies). There was evidence of statistical heterogeneity for the overall analysis (I2=98.1%) and for analyses of studies with a duration of intervention of less than six months (I2=93.5%) and more than two years (I2=99%).
Results were also reported for subgroup analyses and other measures of obesity.