Four studies (1,557 participants) were included in the review: two randomised controlled trials and two observational studies.
Blood pressure (three studies): One observational study reported that 20% of participants in the multidisciplinary care group reached good blood pressure control at follow-up and reached the treatment target (130/80mmHg). One observational study reported significant reductions in systolic and diastolic blood pressure at follow-up for multidisciplinary care in patients without diabetes but no significant differences for patients with diabetes. One RCT reported no significant differences in blood pressure over time or between multidisciplinary care and traditional medical care.
eGFR/CrCL (three studies): One observational study reported a statistically significant decline in eGFR at 12 months post enrolment. Another RCT and one observational study reported no statistically significant differences between groups over time.
Time to renal replacement therapy (one study): One RCT reported a 100% increase in time to renal replacement therapy after a predialysis psycho-educational intervention compared to traditional care.
Metabolic and anaemia control (three studies): One RCT and two observational studies reported increased values and signs of improved control post intervention.
General health and well being (one study): One RCT reported that after a psycho-educational intervention increased knowledge was significantly correlated with delay in renal replacement therapy. No significant differences were reported between groups for depression, anxiety and social support (data not reported).