Assuming lower effectiveness, average cost-effectiveness ratios (cost per additional unit of effectiveness) were presented for each country. Almotriptan: €30.40 in France, €36.93 in Italy, €54.27 in Spain and €23.47 in the UK. Brand-named sumatriptan: €32.42 in France, €26.58 in Italy, €46.92 in Spain and €42.92 in the UK. Generic sumatriptan: €21.92 in France, €22.50 in Italy, €36.67 in Spain and €14.50 in the UK. Zolmitriptan: €42.17 in France, €51.33 in Italy, €51.75 in Spain and €29.17 in the UK.
Assuming higher effectiveness, average cost-effectiveness ratios were presented for each country. Almotriptan: €21.71 in France, €26.38 in Italy, €38.76 in Spain and €16.76 in the UK. Brand-named sumatriptan: €20.47 in France, €16.79 in Italy, €29.63 in Spain and €27.11 in the UK. Generic sumatriptan: €13.84 in France, €14.21 in Italy, €23.16 in Spain and €9.16 in the UK. Zolmitriptan: €25.30 in France, €30.80 in Italy, €31.05 in Spain and €17.50 in the UK.
The ratios varied between countries with differences up to 131% for almotriptan, 77% for brand-name sumatriptan, 153% for generic sumatriptan and 77% for zolmitriptan.