At the programme end, only the Weight Watchers (-2.41, 95% CI -3.6 to -1.23) and Rosemary Conley (-2.22, 95% CI -3.4 to -1.04) programmes recorded a statistically significant reduction in weight compared to the comparator arm of exercise only. At one year, only the Weight Watchers programme recorded a statistically significant reduction in weight (-2.38, 95% CI -3.98 to -0.78). All groups reported increased physical activity at three months follow-up compared to physical exercise alone. Only Weight Watchers reported increased physical activity to compared to the physical exercise only group at one year.
Total costs per patient were £76.87 for Weight Watchers, £71.37 for Slimming World, £76.87 for Rosemary Conley, £91.87 for NHS Size Down Programme, £112.73 for general practice and £112.3 for pharmacy.
Analyses that estimated the effect of gender, programme choice and with adjustments for baseline differences were similar to unadjusted results. Per protocol analysis had similar findings to intention-to-treat analysis. Analysis that compared commercial programmes to one-to-one primary care programmes found that commercial programmes resulted in statistically significantly greater weight loss at three months (p=0.004 unadjusted) and one year (p=0.02 unadjusted, p=0.06 adjusted).